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主要研究方向:
噬菌体制剂的开发与应用;高盐环境、湖泊微生物(噬菌体)多样性和生态功能;噬菌体-宿主相互作用的动态变化及其影响因素和机制。
教育经历:
1. 2006/9–2009/7,中山大学,获博士学位
2. 2003/9–2006/7,suncitygroup太阳集团,获硕士学位
3. 1998/9–2002/7,河北大学,获学士学位
获奖及人才计划
1.罗开珺,李明,肖炜,杨洋,刘甜. 双斑侧沟茧蜂病毒免疫抑制机制,2020年度云南省自然科学二等奖。
2.云南省万人计划“青年拔尖人才”,2018-2023。
3.云南省科技特派员,2014
4.suncitygroup太阳集团“东陆中青年骨干教师”培养计划培养对象,2016.12-2019.12
主持的主要科研项目:
1.湖泊富营养化对浮游病毒与宿主相互关系的影响及机理研究,国家自然科学基金面上项目,58万,2021.1-2024.12
2.高原富营养化湖泊浮游病毒多样性及其对藻类群落的调控,国家自然科学基金地区基金,38万,2017.1-2020.12
3.古老岩盐沉积中的噬菌体多样性及其基因组和宿主域研究,国家自然科学基金青年基金, 23万,2013.01-2015.12
4.云南省微生物资源与系统学公共服务平台建设和技术研发,中央引导地方科技发展专项资金,100万,2018
5.南亚东南亚特色微生物资源保护与利用合作研究基地,云南省重点研发计划项目 (国际科技合作), 100万,2018-2021
6.石林喀斯特碳酸盐矿化菌多样性及其在石材保护中的应用,云南省应用基础研究项目,10万,2014.10-2017.10
代表性论著(第一作者和通讯作者):
1. Diao Kaixin, Li Guohui, Sun Xueqin, Yi Hao , Zhang Shiying,Xiao Wei #. Genomic characterization of a halovirus representing a novel siphoviral cluster. Viruses-Basel. 2023, 15(6), 1392.
2. Yi Hao, Fu Chaoqun, Diao Kaixin, Li Zhiying, Cui Xiaolong*, Xiao Wei*. Characterization and genomic analysis of a novel halovirus infecting Chromohalobacter beijerinckii. Front. Microbiol. 2022, 13: 1041471.
3. Che Raoqiong, BaiMeng, Xiao Wei*, ZhangShiying, WangYongxia, Cui Xiaolong*. Nutrient levels and prokaryotes affect viral communities in plateau lakes, Science of The Total Environment, 2022, 839: 156033.
4. Cheng Yahui, Gao Dongye, Xia Yunsheng, Wang Ziyi, Bai Meng, Luo Kaijun, Cui Xiaolong, Wang Yongxia, Zhang Shiying*, Xiao Wei*. Characterization of Novel Bacteriophage AhyVDH1 and Its Lytic Activity Against Aeromonas hydrophila, Curr Microbiol, 2021,78: 329–337.
5. Bai Meng, Cheng Ya-Hui, Sun Xue-Qin, Wang Zi-Yi, Wang Yong-Xia, Cui Xiao-Long*, Xiao Wei*. Nine Novel Phages from a Plateau Lake in Southwest China: Insignts into Aeromonas Phages Diversity. Viruses-Basel, 2019, 11: 615.
6. Cui, J.-H.#, Dong, S.-M.#, Chen, C.-X.#, Xiao, W.#, Cai, Q.-C., Zhang, L.-D., He, H.-J., Zhang, W., Zhang, X.-W., Liu, T., Ding, L., Yang, Y., Lai, J.-H., Zhu, Q.-S., Luo, K.-J.. Microplitis bicoloratus bracovirus modulates innate immune suppression through the eIF4E-eIF4A axis in the insect Spodoptera litura. Dev. Comp. Immunol.2019, 95: 101-107.
7. Zhang Shiying, Fan Cong, Xia Yunsheng, Li Mengke, Wang Yongxia, Cui Xiaolong, Xiao Wei*. Characterization of a novel bacteriophage specific to Exiguobacterium indicum isolated from a plateau eutrophic lake. J Basic Microbiol. 2019, 59:206-214.
8. Zhang Shiying#, Fan Cong#, Wang Yongxia, Xia Yunsheng, Xiao Wei*, Cui Xiaolong*. Salt-tolerant and plant growth-promoting bacteria isolated from high-yield paddy soil. Canadian Journal of Microbiology, 2018, 64(12): 968-978.
9. Fu Chaoqun ,Zhao Qin ,Li Zhiying ,Wang Yongxia ,Zhang Shiying ,Lai Yonghong ,Xiao Wei* , Cui Xiaolong*. Complete genome sequence of Halomonas ventosae virulent halovirus QHHSV-1. Arch Virol, 2017, 162(10): 3215-3219.
10. Chen Ya-Bin#, Xiao Wei#, Li Ming#, Zhang Yan, Yang Yang, Hu Jian-Sheng, Luo Kai-Jun*. N-terminally elongated SpliInx2 and SpliInx3 reduce baculovirus-triggere apoptosis, via hemichannel closure. Archives of Insect Biochemistry & Physiology, 2016,92(1):24–37.
11. Fu Chao-Qun, Zhao Qin, Li Zhi-Ying, Wang Yong-Xia, Zhang Shi-Ying , Lai Yong-Hong, Xiao Wei*, Cui Xiao-Long*. A novel Halomonas ventosae-specific virulent halovirus isolated from the Qiaohou salt mine in Yunnan, Southwest China. Extremophiles, 2016, 20(1): 101-110.
12. Zhang Shi-Ying#, Xiao Wei#, Xia Yun-Sheng, Wang Yong-Xia, Cui Xiao-Long*, Zhang Nai-Ming*. Arenimonas taoyuanensis sp. nov., a novel bacterium isolated from rice-field soil in China. Antonie van Leeuwenhoek. 2015, 107(5), 1181-1187.
13. Li Ming#, Pang Zunyu#, Xiao Wei#, Liu Xinyi, Zhang Yan, Yu Dongshuai, Yang Minjun, Yang Yang, Hu Jiansheng, Luo Kaijun. A transcriptome analysis suggests apoptosis-related signaling pathways in hemocytes of Spodoptera litura after parasitization by Microplitis bicoloratus, PLoS ONE 2014, 9(10): e110967.
14. Wang Yong-Xia#, Xiao Wei#, Dong Ming-Hua, Zhao Qin, Li Zhi-Ying, Lai Yong-Hong, Cui Xiao-Long. 2014. Halomonas qiaohouensis sp. nov., isolated from salt mine soil in southwest China. Antonie van Leeuwenhoek, 2014, 106(2): 253-260.
15. Xiao Wei, Wang Zhigang; Wang yongxia; Schneegurt Mark A.; Li Zhiying; Lai Yonghong; Zhang Shiying; Wen Mengliang; Cui Xiaolong*. Comparative molecular analysis of the prokaryotic diversity of two salt mine soils in southwest China. J Basic Microbiol, 2013, 53(11): 942-952.
16. Zhao Ming#, Xiao Wei#, Ma Yan ,Sun Tingting, Yuan Wenxia, Tang Na, Zhang Donglian, Wang Yongxia, Li Yali, Zhou Hongjie, Cui Xiaolong,Structure and dynamics of the bacterial communities in fermentation of the traditional Chinese post-fermented pu-erh tea revealed by 16S rRNA gene clone library, World J Microbiol Biotechnol, 2013, 29(10): 1877-1884.
17. Xiao Wei, Wang Yongxia., Liu Jihui, Wang Zhigang, Zhang Xiaoxia, Ji Kaiyan, Lai Yonghong, Wen Mengliang, Cui Xiaolong. Roseivivax sediminis sp. nov., a moderately halophilic bacterium isolated from salt mine sediment. Int J Syst Evol Microbiol. 2012, 62, 1890–1895.
18. Xiao Wei., Yang Yi, Weng QingBei, Yuan, MeiJin, Yang Kai, Pang Yi. The role of the PI3K-Akt signal transduction pathway in Autographa californica multiple nucleopolyhedrovirus infection of Spodoptera frugiperda cells. Virology. 2009, 391: 83-89.
19. 肖炜,张仕颖,赵琴,王永霞,赖泳红,李治滢,崔晓龙,云南个旧锡矿区可培养细菌多样性及其重金属抗性,微生物学报,2013,53(11):1158-1165.
20. 赵琴,任鹏康,王永霞,李治滢,吴鸣,肖炜*,崔晓龙*。云南盐矿中病毒样颗粒的多样性,微生物学报,2015,55(10):1327-1335.
21. 傅超群,白萌,王永霞,李治滢,赖泳红,肖炜*,崔晓龙*。高盐环境可培养细菌噬菌体的研究进展,微生物学通报,2017,44(4):920-928。
22. 张仕颖,董星凡,王永霞,李治滢,赖泳红,崔晓龙,肖炜*。石林喀斯特碳酸钙高效沉积菌的筛选及其沉积条件优化。suncitygroup太阳集团学报(自然科学版),2018, 40(3): 568-576。
23. 李孟珂,夏运生,单壮壮,姬桐,崔晓龙,肖炜*,张仕颖*。三株蓝藻附着细菌多样性及其对铜绿微囊藻增殖的影响,suncitygroup太阳集团学报(自然科学版), 2019, (06): 1238-1245.
24. 张俊锋,李孟珂,吴志浩,崔晓龙,肖炜*,张仕颖*,噬菌体 DCEAV-31 和 DCEIV-9 对溶藻菌溶藻特性的影响,生物技术通报. 2022,38(11):250-257
25. 参编《环境土壤学》(张乃明 主编,中国农业大学出版社,北京,2013. [普通高等教育“十二五”规划建设教材])
26. 参编《云南微生物资源与名录》(张克勤,余泽芬主编,科学出版社,北京,2022)
授权或申请发明专利
(1) 肖炜,崔晓龙,赵琴,王永霞,一种提高微生物可培养性的装置,ZL 201320247504.4。
(2) 肖炜,张仕颖,成亚辉,钟莉瑶,王永霞,崔晓龙。一种噬菌体及其应用,201911093070.5。
教学获奖情况
1. 指导的项目“噬枯灵——高效环保的微生物农药”获第六届中国国际“互联网+”大学生创新创业大赛校级决赛银奖(2020.7)。
2. 荣获第15届suncitygroup太阳集团教师课堂教学比赛优秀奖(2021.11)。
3. 指导的项目“校园不同污水处理厂病毒多样性比较研究”获全国大学生生命科学竞赛(2022,科学探究类)云南赛区二等奖。
4. 指导的项目“校园不同污水处理厂病毒多样性比较研究”获全国大学生生命科学竞赛(2022,科学探究类)国赛三等奖。
5. 指导的项目“菌立噬-高效安全的噬菌体制剂领航者”获suncitygroup太阳集团第九届“互联网+”创新创业大赛创意组金奖(2023.8)。